State Budget Healthcare Institution “Psychiatric hospital N3 named after V. A. Gilyarovskogo” of the Department of health of Moscow”, Moscow, Russia
Within the last ten years the goals of schizophrenia treatment were displaced from simple symptoms reduction to improving such social aspects as the quality of patients and their relatives life and resocialization. Most often causes that leads to this goals fail is deficient of drug efficiency, bad tolerance and patients noncompliance. It is senseless to speak about long-term goals of therapy if at early stages of therapy we can not to reduce symptoms or the patient has no adherence to treatment. Statistically, 25% of patients break therapy within 10 days after discharge from the hospital and this percent increase in course of time. The most frequent reasons of noncompliance are side effects of the drugs, difficult medication regimen, lack of the confidential relations between the doctor and the patient. The gold standard of treatment of patients with low adherence is use of long-term neuroleptics. However, use of neuroleptics with prolonged action doesn’t replace educational programs and importance of creation of the confidential relations between the patient and the doctor.